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HEPATO-PROTECTIVE
Top 10 Hepato Protective Medicine in India- The liver is one of the central organs in the human body which involves cleansing the blood, creating bile for digestion, and controlling nutrients and chemicals within the body. Due to the rising cases of liver injury resulting from unhealthy lifestyles, excessive alcohol consumption, and other infectious agents such as hepatitis, there has been an increasing demand for these liver protective solutions which help to maintain the health of the liver. Gastrointestinal and hepatic support medications improve the functionality of the liver and aid this most important organ in the body carry out its functions effectively.
Silymarin then derived from the seeds of the milk thistle has gained a lot of popularity, especially as a liver-protective herb. It functions as an antioxidant, fighting off free radicals and minimizing the damage caused by them to the cells of the liver. Silymarin additionally promotes protein metabolism thus aiding in the healing of damaged liver tissues and cells. It is common to see Silybon prescribed in cases of liver cirrhosis, hepatitis, and steatosis.
Entecavir is an antiviral medication used in chronic HBV infection. The treatment suppresses the replication of the virus and it is available as tablets and oral solution. It results in reduced viral load, enhanced liver function, and reduced complications caused by the liver. The effective anti-viral activity and significant drug resistance of entecavir make it a potent agent for the treatment of patients who have failed other treatments before. Long-term use reduces inflammation and fibrosis of the liver.
Udiliv preserves the vitality of the hepatocytes as well as the bile ducts by its action on UDCA which is a natural bile acid that improves the flow of bile as well as the viscous bile. Though it can be used for other purposes, it is mainly approved for cholestatic liver diseases like primary biliary cirrhosis and the dissolution of cholesterol gallstones. UDCA works by preventing bile acidic damage to the liver epithelial cells, diminishing inflammation, and promoting liver performance.
L-ornithine-l-aspartate is an exogenous amino acid that promotes the conversion of ammonia to urea in the body. The excess build-up of ammonia can be dangerous, more so, in cirrhosis of the liver, where accumulation can cause hepatic encephalopathy. Due to its ability to lower high levels of ammonia in the organism, Reheptin is used in liver cell regeneration and improvement of its functions. Moreover, it extends benefits to diseases causing acute liver injury and chronic hepatitis.
Evion-LC is a unique combination of Silymarin, L-Carnitine, and Vitamin E, which has antioxidant properties. It aids in preventing the damage of liver cells due to oxidative stress and helps in liver cell regeneration. In addition, L-carnitine facilitates fat metabolism, which benefits patients suffering from non-alcoholic fatty liver disease preferably known as NAFLD. Vitamin E serves to enhance this effect by preventing free radical attacks from damaging the liver.
Obeticholic Acid is a synthetic bile acid analog used to treat liver diseases like primary biliary cholangitis and non-alcoholic steatohepatitis. It activates the farnesoid X receptor (FXR) to reduce inflammation and improve liver function. It's a second-line treatment for PBC patients and is being investigated for treating NASH-associated liver fibrosis. However, side effects like itching, fatigue, abdominal pain, and diarrhea may occur.
Cirrosam 400 Tablet is a hepatoprotective drug that is introduced to the body for the support of liver function in the treatment of a variety of disorders such as cirrhosis, fatty liver, and cholestasis. The dosage of 400 mg once or twice a day orally causes the possibility of side effects like nausea and headaches.
Glutathione is an endogenous antioxidant found in the liver. It has been known to detoxify harmful substances and protect cells of the liver from oxidative damage. Glutathione supplements, especially Livergen, are very commonly prescribed in cases of non-alcoholic fatty liver disease, chronic hepatitis, as well as those types of damage to the liver caused by alcohol or drugs. Its administration aids in maintaining the health of the liver. The supplement induces the detoxification process and regenerates the cells of the organ.
One class of lipids known as phospholipids constitute a basic constituent of cell membranes, which are the building and structural scaffolding of cells in the body. There exist molecules consisting of a glycerol backbone and two fatty acid tails that are hydrophobic and a phosphate group head that is hydrophilic. The structure of phospholipids enables them to form bilayers; this is an essential aspect for maintaining integrity as well as the functionality of the cell membrane. Cellular signaling and metabolism are also in large measure influenced by phospholipids.
Below we share the list of the top 10 Hepato Protective Medicine in India-
1. Heptra with an active ingredient Ademetionine boasts a milligram content of 400mg.
Heptral incorporates ademetionine, a substance synthesized in the body and primarily in the liver. It is an active participant in the metabolism of several constituents, and cellular detoxification processes and helps maintain the integrity of cell cellular structures. Ademetionine is also indicated for therapeutic interventions in primary liver diseases including but not limited to - cirrhosis, non-alcoholic fatty liver disease, and medication-associated liver injury. Heptral has been shown to possess antioxidant and anti-inflammatory properties which enhance the recovery process of the liver from injury.2. Silybon (Silymarin)
Composition: Silymarin 140 mgSilymarin then derived from the seeds of the milk thistle has gained a lot of popularity, especially as a liver-protective herb. It functions as an antioxidant, fighting off free radicals and minimizing the damage caused by them to the cells of the liver. Silymarin additionally promotes protein metabolism thus aiding in the healing of damaged liver tissues and cells. It is common to see Silybon prescribed in cases of liver cirrhosis, hepatitis, and steatosis.
3. Entecavir
Composition: Entecavir 5mgEntecavir is an antiviral medication used in chronic HBV infection. The treatment suppresses the replication of the virus and it is available as tablets and oral solution. It results in reduced viral load, enhanced liver function, and reduced complications caused by the liver. The effective anti-viral activity and significant drug resistance of entecavir make it a potent agent for the treatment of patients who have failed other treatments before. Long-term use reduces inflammation and fibrosis of the liver.
4. Udiliv (Ursodeoxycholic Acid)
Composition: Ursodeoxycholic Acid (300 mg)Udiliv preserves the vitality of the hepatocytes as well as the bile ducts by its action on UDCA which is a natural bile acid that improves the flow of bile as well as the viscous bile. Though it can be used for other purposes, it is mainly approved for cholestatic liver diseases like primary biliary cirrhosis and the dissolution of cholesterol gallstones. UDCA works by preventing bile acidic damage to the liver epithelial cells, diminishing inflammation, and promoting liver performance.
5. Reheptin (L-Ornithine-L-Aspartate)
Composition: L-Ornithine-L-Aspartate (5g).L-ornithine-l-aspartate is an exogenous amino acid that promotes the conversion of ammonia to urea in the body. The excess build-up of ammonia can be dangerous, more so, in cirrhosis of the liver, where accumulation can cause hepatic encephalopathy. Due to its ability to lower high levels of ammonia in the organism, Reheptin is used in liver cell regeneration and improvement of its functions. Moreover, it extends benefits to diseases causing acute liver injury and chronic hepatitis.
6. Evion-LC (Silymarin, L-Carnitine, Vitamin E)
Composition: Silymarin (70 mg), L-Carnitine (330 mg), Vitamin E (400 mg)Evion-LC is a unique combination of Silymarin, L-Carnitine, and Vitamin E, which has antioxidant properties. It aids in preventing the damage of liver cells due to oxidative stress and helps in liver cell regeneration. In addition, L-carnitine facilitates fat metabolism, which benefits patients suffering from non-alcoholic fatty liver disease preferably known as NAFLD. Vitamin E serves to enhance this effect by preventing free radical attacks from damaging the liver.
7. Obeticholic Acid
Composition- (Obeticholic Acid 10 mg)Obeticholic Acid is a synthetic bile acid analog used to treat liver diseases like primary biliary cholangitis and non-alcoholic steatohepatitis. It activates the farnesoid X receptor (FXR) to reduce inflammation and improve liver function. It's a second-line treatment for PBC patients and is being investigated for treating NASH-associated liver fibrosis. However, side effects like itching, fatigue, abdominal pain, and diarrhea may occur.
8. Cirossam
Composition- Cirrosam 400mgCirrosam 400 Tablet is a hepatoprotective drug that is introduced to the body for the support of liver function in the treatment of a variety of disorders such as cirrhosis, fatty liver, and cholestasis. The dosage of 400 mg once or twice a day orally causes the possibility of side effects like nausea and headaches.
9. Glutathione
Composition- Glutathione (600 mg to 1200mg)Glutathione is an endogenous antioxidant found in the liver. It has been known to detoxify harmful substances and protect cells of the liver from oxidative damage. Glutathione supplements, especially Livergen, are very commonly prescribed in cases of non-alcoholic fatty liver disease, chronic hepatitis, as well as those types of damage to the liver caused by alcohol or drugs. Its administration aids in maintaining the health of the liver. The supplement induces the detoxification process and regenerates the cells of the organ.
10. Phospholipids
Composition: Phospholipids (300 mg)One class of lipids known as phospholipids constitute a basic constituent of cell membranes, which are the building and structural scaffolding of cells in the body. There exist molecules consisting of a glycerol backbone and two fatty acid tails that are hydrophobic and a phosphate group head that is hydrophilic. The structure of phospholipids enables them to form bilayers; this is an essential aspect for maintaining integrity as well as the functionality of the cell membrane. Cellular signaling and metabolism are also in large measure influenced by phospholipids.